Basic Assurans Information

• INN (International Nonproprietary Name): Sildenafil Citrate
• Brand Names Available in Canada: Assurans
• ATC Code: G04BE03 (for erectile dysfunction), C02KX05 (for pulmonary arterial hypertension)
• Forms & Dosages: 20 mg tablets
• Manufacturers in Canada: Cipla Ltd.
• Registration Status in Canada: Prescription only
• OTC / Rx Classification: Prescription Only (Rx)

Availability & Price Landscape

When it comes to finding Assurans in Canada, several major pharmacy chains are reliable options. Shoppers Drug Mart, Rexall, and London Drugs are among the most popular places where Assurans is stocked. These chains have locations across many provinces, ensuring that a significant portion of the population can access this essential medication. Whether you are in urban hubs like Toronto or Vancouver, or more suburban areas, these pharmacies aim to provide widespread availability.

Online Pharmacy Trends In Canada

With the rise of digital shopping, online pharmacies have also surged in popularity. Many Canadians are opting for the convenience of purchasing Assurans online. However, it's essential to be aware of provincial regulations that can affect these purchases. Some provinces, such as Ontario and British Columbia, have specific guidelines governing the sale of prescription medications online. These regulations often require that an initial consultation with a healthcare professional occurs before ordering medications like Assurans. This protective measure helps ensure patient safety while also allowing greater accessibility.

Price Ranges By Package Size

Price can vary significantly across provinces and pharmacies when it comes to Assurans. Generally, a package of 20 mg tablets of Assurans will sit within a certain price range, but here's what to expect:

• In British Columbia, you might find prices ranging from CAD $35 to $50 for a month’s supply.
• Ontario prices can be a bit lower, typically falling between CAD $30 and $45.
• Out in the Prairies, like Alberta and Saskatchewan, costs may rise slightly due to transportation and availability, with averages around CAD $40 to $55.

Factors that influence these prices include regional supply levels, pharmacy markups, and if any local promotions are running. Additionally, patients may find better deals through bulk purchase options, especially when shopping online.

In summary, the landscape for Assurans in Canada shows a robust availability through major pharmacies and the growing trend of online purchases, coupled with diverse pricing structures. As the market continues evolving, being informed about your options can greatly benefit consumers locally.

Dosage & Administration

Standard regimens per Canadian guidelines

Health Canada outlines specific dosing schedules for Assurans (sildenafil citrate) that focus on various conditions, predominantly pulmonary arterial hypertension (PAH).

The standard dosage for PAH in adults is 20 mg, administered three times daily, with doses taken evenly throughout the day. This regimen can be adjusted based on clinical response and tolerance.

While Assurans is not typically indicated for erectile dysfunction, some physicians may prescribe 50 mg as needed; however, this use is less common in the Canadian setting.

Adjustments by patient type (with Canadian clinical notes)

Patients may require specific dosage adjustments based on individual health conditions. Here are some key considerations:

• Children: For those aged one year and older with PAH, dosages range from 10 to 20 mg, taken three times daily, depending on body weight.
• Senior patients: Generally, no initial dose is required, but starting at the lowest effective dose is advised and should be closely monitored.
• Hepatic impairment: Caution is needed in moderate cases, and Assurans should be avoided in severe conditions.
• Renal impairment: Mild to moderate cases can manage dosing with caution, but severe impairment necessitates avoidance or careful starting at a low dose.

Contraindications & Side Effects

Common (Health Canada-approved list)

Understanding the potential side effects of Assurans is crucial for patient safety. Common side effects include:

• Headaches
• Flushing
• Nasal congestion
• Dyspepsia
• Visual disturbances

These effects are generally mild to moderate. However, it is advisable to consult a healthcare professional if they persist or worsen.

Rare but serious (with Canadian pharmacovigilance data)

While adverse effects are mostly mild, certain rare but serious complications may arise. Some of these include:

• Severe hypotension, particularly in patients taking nitrate medications
• Priapism, a prolonged and painful erection that may require surgical intervention
• Visual disturbances, such as sudden loss of vision
• Cardiovascular complications, including heart attack or stroke in predisposed individuals

Clinicians in Canada should maintain awareness of these severe effects recorded in pharmacovigilance data to ensure patient safety and timely management.

Comparable Medicines in Canada

Alternatives table (with DIN references)

Pros and cons list

When considering Assurans versus other medications for PAH and erectile dysfunction, here’s a quick overview:

• Pros: - Generally well-tolerated and effective for PAH - Cost-effective for many patients - Multiple dosing options available.
• Cons: - Limited use in erectile dysfunction; not first-line treatment - Potential side effects that can affect quality of life - Requires monitoring especially in special populations.

Current Research & Trends

Major Canadian or international studies 2022–2025

Recent studies have focused on the efficacy of Assurans in treating pulmonary arterial hypertension, with findings displayed at key conferences. Canadian researchers have demonstrated notable improvements in exercise capacity and quality of life for PAH patients using Assurans in standard regimens.

Additionally, ongoing international trials are exploring combination therapies that include Assurans, aimed at enhancing treatment efficacy while managing side effects. The trend is toward personalized medicine, tailoring treatments based on patient profiles and responses.

Common Patient Questions in Canada

Patients often have legitimate concerns regarding Assurans. Here are some commonly asked questions:

• How is Assurans taken? Typically taken three times daily for PAH, with dosage adjustments as necessary based on individual health.
• Is it safe? Generally safe under doctor supervision, but patients with specific health issues should consult a clinician.
• What about cost and availability? Assurans is available through pharmacies and can often be purchased without a receipt, although a prescription is recommended for safe use.

Regulatory Status

Assurans, the brand name for Sildenafil Citrate, has successfully navigated Health Canada's rigorous approval process to be made available for Canadian patients. This involves a comprehensive evaluation of clinical data, efficacy, and safety to ensure that the medication meets national health standards. Once the product meets the clinical benchmarks, it receives a license, allowing it to be prescribed for managing pulmonary arterial hypertension (PAH). The registration as a prescription-only medication highlights the necessity for medical oversight in its use.

DIN number relevance

The Drug Identification Number (DIN) is crucial in the Canadian healthcare landscape as it identifies approved medications, including Assurans. Each drug with a DIN is vetted for quality and safety. For patients and healthcare practitioners, this number serves as a guarantee that the medication is safe for use, tracked for any potential side effects, and compliant with Canadian regulations. The DIN allows pharmacists to ensure that the medication dispensed is genuine, aiding in patient safety and regulatory adherence.

Visual Recommendations

Infographics can be an engaging way to convey important information about Assurans. Potential ideas include:

• A visual representation comparing the effectiveness of Assurans to other medications used for PAH, highlighting common dosages and delivery methods.
• An infographic showing the side effects associated with Assurans, ensuring patients are well-informed before use.
• A timeline-style graphic that outlines the Health Canada approval process, showing how long it takes for a drug like Assurans to become available post-research and trials.

These visuals can provide clarity, making complex medical information accessible and understandable for patients and healthcare professionals alike.

Buying & Storage Advice

For purchasing Assurans, both in-store and online options are available in Canada. In-store purchases allow patients to consult directly with pharmacists, ensuring they gain advice specific to their needs. However, online options offer convenience and often competitive pricing. When buying online, it's crucial to use reputable sources, particularly those that require a prescription, ensuring the authenticity of the product.

Considering the diverse Canadian climate, proper storage of Assurans is vital. It should be kept in its original packaging, shielded from moisture and direct sunlight, and ideally stored at temperatures below 30°C (86°F). During colder winters or humid summers, ensuring proper conditions can help maintain the medication's effectiveness. It's important to avoid refrigeration or freezing, as that can compromise its formulation.

Guidelines for Proper Use

Healthcare professionals recommend specific best practices for administering Assurans to ensure safety and effectiveness. Here's a concise guide:

• Start with the lowest effective dose to assess tolerance.
• Take Assurans approximately 30 minutes to an hour before meals for optimal absorption.
• Do not exceed the maximum recommended dose, particularly in patients with co-existing medical conditions.
• Regular consultations with a healthcare provider will ensure the continued effectiveness and safety of the medication.

The insights from Canadian healthcare professionals emphasize the importance of monitoring individual responses to the medication, ensuring adjustments are made as needed for optimal patient care.