Basic Uniphyl CR Information

• INN (International Nonproprietary Name): Theophylline
• Brand names available in Canada: Uniphyl, Theolair
• ATC Code: R03DA04
• Forms & dosages: Extended-release tablets, 300 mg, 400 mg
• Manufacturers in Canada: Medicis and various generic manufacturers
• Registration status in Canada: Prescription (Rx)
• OTC / Rx classification: Prescription only

Availability & Price Landscape

Uniphyl CR, a well-known medication for managing respiratory conditions, is readily available across Canada. Major national pharmacy chains like Shoppers Drug Mart, Rexall, and London Drugs stock Uniphyl CR, ensuring accessibility for patients who require this medication. It is advisable to check with specific locations for in-stock availability, as some stores may experience variations in inventory.

Online Pharmacy Trends in Canada

The trend of purchasing medications online has seen significant growth in Canada, particularly following the COVID-19 pandemic. Many patients are turning to online pharmacies for convenience and often better pricing. However, it is crucial to be aware of provincial regulations governing online prescriptions and medication distribution. Some provinces may impose restrictions on who can prescribe medications online, and not all online pharmacies are licensed or regulated effectively, which can pose risks to patients.

Price Ranges by Package Size

The price of Uniphyl CR can vary widely based on location, type of pharmacy, and package size. Below is a general comparison:

• In-store prices at large chains typically range from CAD 50 to CAD 120, depending on dosage and quantity.
• Online pharmacies may offer prices that are slightly lower, potentially ranging from CAD 45 to CAD 115.

Provincial differences also play a role in pricing; for instance, the cost may be higher in more remote areas compared to urban centres where competition among pharmacies is more significant. Patients are encouraged to shop around and compare prices both online and in-store to ensure they receive the best deal on their medication.

Dosage & Administration

Standard regimens per Canadian guidelines

When it comes to theophylline dosing for conditions like asthma or COPD in Canada, there are some established norms to keep in mind.

For adults, the typical recommendation is:

• 300 mg to 600 mg per day, usually via extended-release formulations like Uniphyl CR, with either a single morning dose or divided into two doses.

For children, the dosage is more nuanced:

• Typically starts at 10–13 mg/kg per day, in divided doses, with regular monitoring of serum levels being crucial.

Adjustments by patient type (with Canadian clinical notes)

Some patients may require tailored adjustments for effective and safe treatment. The elderly, for instance, are generally more sensitive and may need to start at the lower end of dosing.

When it comes to liver impairment, caution is essential as the medication's clearance drops, necessitating a dosage reduction to avoid toxicity.

For renal impairment, adjustments in dosage are also necessary to mitigate the increased risk of adverse effects.

Contraindications & Side Effects

Common (Health Canada-approved list)

Like any medication, Uniphyl CR is not without its potential side effects. According to Health Canada, some common ones include:

• Nausea and vomiting
• Headaches
• Heartburn
• Insomnia and restlessness

Most patients experience mild to moderate reactions, which may require communication with healthcare providers for monitoring and support.

Rare but serious (with Canadian pharmacovigilance data)

There are rare but serious adverse effects linked to Uniphyl CR that warrant attention. Adverse reactions such as heart palpitations, seizures, or significant arrhythmias have been documented.

Health Canada engages in constant pharmacovigilance to monitor these severe reactions, ensuring patient safety remains a priority.

Comparable Medicines in Canada

Alternatives table (with DIN references)

Pros and cons list

Considering Uniphyl CR against alternatives, it has both upsides and drawbacks:

• Pros: Extended-release form allows for once-daily dosing, beneficial for maintenance therapy.
• Cons: It has a narrow therapeutic index, increasing the risk of toxicity compared to inhaled alternatives.

Current Research & Trends

Major Canadian or international studies 2022–2025

Recent studies from 2022 to 2025 continue to examine the efficacy of theophylline, including Uniphyl CR. Research highlights its effectiveness when combined with other therapies in improving lung function and reducing exacerbation rates in chronic respiratory conditions.

Some trials are also exploring new applications, showing potential benefits in other medical areas beyond traditional uses. Observations suggest a resurgence in interest toward theophylline derivatives, particularly within contexts of combination treatments.

Common Patient Questions in Canada

Frequently Asked Questions about Uniphyl CR

Patients often seek clarity regarding Uniphyl CR. Here are some key questions and straightforward answers:

• How should I take Uniphyl CR? It's typically taken once daily, as directed by your healthcare provider.
• What if I miss a dose? Take it as soon as you remember, but never double up if the next dose is near.
• What side effects should I be aware of? Common side effects include nausea and headaches; inform your doctor if they worsen.

For any concerns or specific scenarios, always consult a healthcare professional to tailor advice to personal health needs.

Regulatory Status

Health Canada Approval Process

Understanding the approval process for Uniphyl CR in Canada starts with Health Canada's rigorous evaluation system. This process ensures that only safe and effective medications reach the market. For Uniphyl CR, data regarding its efficacy and safety must be submitted, including results from clinical trials and studies.

The submission is reviewed by Health Canada, which assesses the risks and benefits associated with the drug. If approved, the medication will be assigned a Drug Identification Number (DIN) before becoming available to the public. This comprehensive evaluation guarantees that healthcare professionals and patients can trust the therapeutic claims.

DIN Number Relevance

The Drug Identification Number (DIN) plays a crucial role in the context of Uniphyl CR. This unique 8-digit number provides a way for healthcare professionals and pharmacies to identify the specific formulation of a drug quickly, ensuring accuracy in prescribing and dispensing.

A DIN signifies that the product has been approved by Health Canada and has passed rigorous safety and effectiveness standards. For consumers, it’s a peace-of-mind marker, asserting that the medication has undergone stringent testing and is fit for use.

Visual Recommendations

Infographic Ideas for Canadian Context

Creating engaging infographics can be a powerful tool for educating patients about Uniphyl CR. Here are a few concepts tailored to the Canadian context:

• Usage Guidelines: Illustrate how to take Uniphyl CR correctly, including dosages and timing.
• Side Effects Overview: A visual chart showcasing common and serious side effects can help inform patients when they should seek medical attention.
• Climate Considerations: An infographic highlighting proper storage tips in various Canadian climates can ensure that patients maintain the drug's effectiveness.
• Comparison with Alternatives: A side-by-side comparison of Uniphyl CR with other asthma medications can help patients understand their choices and potential benefits.

Buying & Storage Advice

In-store vs. Online Canadian Purchase Tips

Canadians looking to purchase Uniphyl CR can find options both in-store and online. Here’s what to consider:

• In-Store: Always consult with a pharmacist to clarify any questions about the dosage or potential interactions with other medications.
• Online: When buying Uniphyl CR online, ensure you are using a legitimate pharmacy to avoid counterfeit products. Look for an online pharmacy that requires a prescription, even if a prescription is not always legally required in Canada.

Proper Storage with Canadian Climate Considerations

Uniphyl CR should be stored correctly to maintain its effectiveness. Canadian climates can vary greatly; here are some storage guidelines to consider:

• Keep the medication at room temperature, between 20–25 °C (68–77 °F).
• In colder environments, ensure that Uniphyl CR is kept away from moisture and extreme cold to prevent degradation.
• Avoid leaving it in a sunny spot or in a hot vehicle, as heat can compromise the drug's integrity.

Guidelines for Proper Use

Canadian Doctor/Pharmacist Advice Style

When using Uniphyl CR, following best practices can lead to better management of asthma or COPD:

• Follow Prescriptions: Always take the medication as prescribed by a healthcare professional, usually once daily in its extended-release form.
• Monitor Symptoms: Keep track of asthma or COPD symptoms; report any sudden changes or side effects to your healthcare provider.
• Avoid Overuse: If a dose is missed, take it as soon as remembered unless close to the next scheduled dose.
• Regular Check-Ups: Periodically review your treatment plan with a healthcare professional, especially for children and the elderly, who may require adjusted dosages.

Delivery Times by City